Publications
Drosophila Drap1 corepressor associating with dCtBP mediates short-range repression (in preparation).
Aihara H*, Stern MD*, Roccaro GA, Sun J, Nibu Y. Differential properties between long and short isoforms of Drosophila CtBP, dCtBP. (in preparation). *equally contributed.
Aihara H, Stern MD, Ito T, Nibu Y. The dCtBP corepressor selectively inhibits adjacent activators through the dCBP coactiovator (in preparation).
Stern MD, Aihara H, Roccaro GA, Cheung L, Zhang H, Negeri D, Nibu Y. CtBP is required for proper development of peripheral nervous system in Drosophila. Mech. Dev. 126, 68-79 (2009).
Stern MD, Aihara H, Cho KH, Kim GT, Horiguchi G, Roccaro GA, Guevara E, Sun HH, Negeri D, Tsukaya H, Nibu Y. Structurally related Arabidopsis ANGUSTIFOLIA is functionally distinct from the transcriptional corepressor CtBP. Dev Genes Evol., 217(11-12):759-769 (2007).
Qi D, Bergman M, Aihara H, Nibu Y, Mannervik M. Drosophila Ebi mediates Snail-dependent transcriptional repression through HDAC3-induced histone deacetylation. EMBO J. 27, 898-909 (2008).
Lilja T, Aihara H, Stabell M, Nibu Y, Mannervik M. The acetyltransferase activity of Drosophila CBP is dispensable for regulation of the Dpp pathway in the early embryo. Dev Biol., 305, 650-658 (2007).
Aihara H, Perrone L, Nibu Y. Transcriptional repression by the CtBP corepressor in Drosophila. In: CtBP Family Proteins (ed. D. Chinnadurai), Chapter 2, p18-27, Landes Bioscience, Georgetown, TX, (2006).
Perrone L, Aihara H, Nibu Y. Transcriptional repressors and repression mechanisms. In: Gene Expression and Regulation (ed. J. Ma), Chapter 09, p159-173, a Current Scientific Frontiers Book, Higher Education Press, Beijing, (2006).
Date, S., Nibu, Y., Yanai, K., Hirata, J., Yagami, K., and Fukamizu, A. Finb, a multiple zinc finger protein, represses transcription of the human angiotensinogengene. Int. J. Mol. Med. 13, 637-642 (2004).
Nibu, Y., Senger, K., and Levine, M. CtBP-independent repression in the Drosophila embryo. Mol. Cell. Biol. 23, 3990-3999 (2003).
Berman, BP., Nibu, Y., Pfeiffer, BD., Tomancak, P., Celniker, SE., Levine, M., Rubin, GM., and Eisen, MB. Exploiting transcription factor binding site clustering to identify cis-regulatory modules involved in pattern formation in the Drosophila genome. Proc. Natl. Acad. Sci. USA 99, 757-762 (2002).
Nibu, Y. and Levine, M. CtBP-dependent activities of the short-range Giant repressor in the Drosophila embryo. Proc. Natl. Acad. Sci. USA 98, 6204-6208 (2001).
Nibu, Y., Zhang, H., and Levine, M. Local action of long-range repressors in the Drosophila embryo. EMBO J. 20, 2246-2253 (2001).
Mannervik M, Nibu Y, Zhang H, and Levine M. Transcriptional coregulators in development. Science. 284, 606-609 (1999).
Yanai, K., Hirota, K., Taniguchi-Yanai, K., Shigematsu, Y., Shimamoto, Y., Saito, T., Chowdhury, S., Takiguchi, M., Arakawa, M., Nibu, Y., Sugiyama, F., Yagami, K., and Fukamizu, A. Regulated expression of human angiotensinogen gene by hepatocyte nuclear factor 4 and chicken ovalbumin upstream promoter-transcription factor. J. Biol. Chem. 274, 34605-34612 (1999).
Nibu, Y., Zhang, H., Bajor, E., Barolo, S., Small, S., and Levine, M. dCtBP mediates transcriptional repression by Knirps, Krüppel and Snail in the Drosophila embryo. EMBO J. 17, 7009-7020 (1998).
Nibu, Y., Zhang, H., and Levine, M. Interaction of short-range repressors with Drosophila CtBP in the embryo. Science 280, 101-104 (1998).
Takeuchi, T., Nibu, Y., Murata, K., Yoshida, S., and Kusakabe, I. Characterization of a novel alginate lyase from Flavobacterium multivolum K-11. Food Sci. Technol. Int. 3, 288-392 (1997).
Takeuchi, T., Nibu, Y., Murata, K., and Kusakabe, I. Purification and characterization of endo poly (alphaL-guluronate) lyase in the enzyme system from Flavobacterium multivolum. Food Sci. Technol. Int. 3, 22-26 (1997).
Tanimoto, K., Yoshida, E., Mita, S., Nibu, Y., Murakami, K., and Fukamizu, A. Human Activin beta A gene. Identification of novel 5' exon, functional promoter, and enhancers. J. Biol. Chem. 271, 32760-32769 (1996).
Yanai, K., Nibu, Y., Murakami, K., and Fukamizu, A. A cis-acting DNA element located between TATA box and transcription initiation site is critical in response to regulatory sequences in human angiotensinogen gene. J. Biol. Chem. 271, 15981-15986 (1996).
Kobayashi, S., Ohnishi, J., Nibu, Y., Nishimatsu, S., Umemura, S., Ishii, M., Murakami, K., and Miyazaki, H. Cloning of the rat angiotensin II type 2 receptor gene and identification of its functional promoter region. Biochim. Biophys. Acta 1262, 155-158 (1995).
Nibu, Y., Satoh, T,. Nishi, Y., Takeuchi, T,. Murata, K., and Kusakabe, I. Purification and characterization of extracellular alginate lyase from Enterobacter cloacae M-1. Biosci. Biotech. Biochem. 59, 632-637 (1995).
Nibu, Y., Tanimoto, K., Takahashi, S., Ono, H., Murakami, K., and Fukamizu, A. A cell type-dependent enhancer core element is located in exon 5 of the human angiotensinogen gene. Biochem. Biophys. Res. Commun. 205, 1102-1108 (1994).
Nibu, Y., Takahashi, S., Tanimoto, K., Murakami, K., and Fukamizu, A. Identification of cell type-dependent enhancer core element located in the 3'-downstream region of the human angiotensinogen gene. J. Biol. Chem. 269, 28598-28605 (1994).